Classification of antifungal tablets
Tablet drugs with antimycotic action vary depending on the structure and mechanism of action.
Polyenequickly destroys fungal spores by disrupting the integrity of their membranes. They are well received by the body and do not have a negative effect on the liver and digestive system.
To treat fungal infections in the early stages, external drugs are used - solutions, varnishes or creams, hydrogen peroxide.
It is recommended to treat the fungus with tablets when ointments, creams, oils, sprays and other topical agents do not bring any results.
Tablets are effective for nail fungus
The pharmacological market offers a wide variety of antifungal drugs in tablet form, differing in the main active ingredient, manufacturer and cost.
Active ingredients:
- Terbinafine hydrochloride
- Fluconazole
- Terbinafine
- Ketoconazole
- Itraconazole
- Griseofulvin
- Itraconazole
- Ketoconazole
- Terbinafine
- Natamycin
When choosing a drug, you must take into account the type of fungal infection and the severity of the disease. Before starting therapy, it is necessary to correctly determine the nature of onychomycosis, because many drugs only affect certain groups of pathogens.
Medicines based on terbinafine hydrochloride
This is a tablet antifungal drug that has a pathogenic effect on pathogenic microorganisms that cause onychomycosis. Contains active ingredients with the same name. This product helps destroy the outer membrane of the fungal pathogen, which leads to its death.
Inexpensive tablets are used to treat onychomycosis, dermophytosis, and ringworm.
- kidney failure;
- children under 3 years of age;
- period of pregnancy and breastfeeding;
- hypersensitivity to terbinafine.
This medicine can cause side effects - headache, nausea, loss of appetite, painful stools, painful stomach cramps.
With long-term use, you need to systematically monitor liver function and stop drinking alcoholic beverages.
The recommended dose is 1 tablet per day. The duration of treatment is determined individually. In advanced stages of onychomycosis, use is allowed for 8-12 weeks.
Medicines from the group of triazole antifungal agents
Effective drugs with antifungal action, produced in various pharmacological forms. This drug is used to eliminate fungal infections, as well as for preventive purposes. It is allowed to be used for liver diseases, but under the supervision of a doctor.
- kidney disease;
- the period of exacerbation of psoriasis and other dermatological diseases of an inflammatory nature;
- pregnancy;
- individual intolerance to the active component in Fluconazole.
To treat nail fungus, the drug is taken once a day for 4 weeks. After this, the dose is reduced to 1 tablet every 7 days. This product has a cumulative effect - after 4-5 days of use, a high concentration of the substance accumulates in the stratum corneum of the nail plate.
To avoid remission, the drug must be taken until the healthy nail plate has fully grown.
In rare cases, the drug causes side effects such as nausea, stomach pain, itching and burning in the area affected by the fungus, and various allergic reactions.
Medicine based on terbinafine hydrochloride 10 mg
This is an antimycotic drug that is very effective against many types of fungal microorganisms. The active ingredient terbinafine inhibits the biosynthesis of sterols in fungal cells, which leads to the rapid death of infectious agents.
This drug is well tolerated by the body and has a minimal number of contraindications for use - severe forms of kidney disease, increased sensitivity to the active components included in its composition. Approved for use in liver disease.
For adults, it is recommended to take 1 tablet a day for 3-6 weeks. To cure the advanced stages of toenail fungus, the duration of the therapeutic course is increased to 10-12 weeks.
In very rare cases, it causes headache, nausea, fullness in the stomach, allergic manifestations, and skin rashes.
Medicines based on ketoconazole
Ketoconazole is one of the most powerful antifungal agents. It is used for severe, advanced systemic fungal infections.
Use is recommended for total damage to the nail plate, which also affects the nearby soft tissue. Also, the drug is prescribed if antimycotic drugs for topical use do not bring positive results.
Approved for use in liver disease, but best under the supervision of a doctor and regular liver tests.
This medicine should not be used to treat nail fungus in children under 12 years of age, pregnant and lactating women, as well as individual intolerance.
Side effects: attacks of nausea and vomiting, flatulence and abdominal pain, conjunctivitis, allergic skin rashes, apathy, nervousness, in men - a temporary decrease in libido.
The recommended dose for onychomycosis is 1-2 tablets per day, depending on the severity of the fungal infection. The duration of therapy is 4-5 weeks.
Preparation based on itraconalose 0. 1 g
The ingredient itraconazole is used in inexpensive medications for toenail fungus. It inhibits ergosterol in the cell membrane of pathogenic microorganisms and has an adverse effect on almost all known nail fungus pathogens. Tablets containing intraconazole are used to treat fungal infections, regardless of the location and extent of the lesion.
The drug should not be used in cases of exacerbation of kidney disease, as well as hypersensitivity to the active components included in its composition. For liver disease, it is used during the remission period.
Cheap and effective drugs can cause negative reactions - the development of dysbiosis, flatulence, pain in the stomach, headache and dizziness. In rare cases, the drug can cause soft tissue swelling.
To treat nail onychomycosis, it is recommended to take 1 tablet in the morning and evening for 10-12 weeks. After this, the drug is taken in a weekly course with a break of 2-3 weeks.
Medicines based on itraconalose
The antimycotic effect of the drug is provided by the active ingredient itraconazole. For fungal infections of nails and toenails, the medicine is taken 2 tablets once a day, or by dividing the dose into two doses. The duration of treatment is from 8 to 12 weeks.
At home can also be used for weekly therapy. After taking the tablets for 7 days, take a break for 3 weeks, after which the treatment is continued. For fungal infections of the nail plate, at least 3 courses are required. Tablets are taken in 2 pieces, morning and evening.
This medicine is well received by the body. In rare cases, side effects may occur - nausea, constipation, allergic skin rash, headache, loss of appetite, nervousness, fatigue, loss of strength. In case of exacerbation of liver disease, use with caution.
Drug based on itraconazole 100 mg
The antimycotic drug contains the active ingredient itraconazole 100 mg, which has a damaging effect on the fungal membrane and leads to the death of pathogenic microorganisms. It is a broad-spectrum drug, which is why it is prescribed for advanced stages of onychomycosis.
Medicines should not be taken in case of heart failure or low level of sucrose in the blood. Medicines should be taken very carefully if you have fructose intolerance.
For fungal nail infections, it is recommended to take 1 tablet in the morning and evening, 20-30 minutes after a meal. The average course of treatment is 2-3 weeks. Reception is stopped only after the healthy nail plate grows back.
Taking the drug may be accompanied by side effects - nausea, vomiting, stools, loss of appetite, headache, dizziness, peripheral neuropathy, skin rash. In some cases, women may experience irregular periods. In case of exacerbation of liver disease, use with caution.
Drug based on ketoconazole 200 mg
This is a broad-spectrum drug with antimycotic and antibacterial effects. The main active component in the product is ketoconazole, which is very effective against dermatophytes, eumycetes, dimorphic and yeast fungal pathogens.
To treat fungal nail disease, it is recommended to take 1-2 tablets throughout the day. The exact dose of the drug is determined by the doctor depending on the severity of the disease. The average duration of the therapeutic course is 12-15 weeks.
Medicines should not be taken during pregnancy, breastfeeding, or for the treatment of children under the age of 3 years.
In case of exacerbation of liver disease, use with caution. Tablets can cause negative reactions from internal organs - upset stool, nausea, vomiting, skin rash, drowsiness, loss of strength.
Drug use in men in some cases is accompanied by a decrease in sexual activity and erectile dysfunction, which negatively affects intimate life.
A brief summary
Effective and inexpensive antimycotic drugs, produced in the form of tablets, are used for fungal infections of the nail plate of various origins. They are prescribed when ointments, gels and other means of external application do not bring the desired results.
Broad-spectrum tablets are effective against most pathogenic microorganisms and fungal pathogens. Treatment of mycosis is long and complex; medication must be taken until the healthy nail plate grows back.
Effective antifungal medication
Are your nails turning yellow and peeling, do you have dandruff, or are you overcome by thrush? All these are symptoms of a fungal infection, which means that treatment is very necessary. Let's talk to experts about effective antifungal drugs and how to choose them correctly
Mycoses or fungal infections are very common diseases. Fungus usually affects the skin, mucous membranes and nails, but can also affect internal organs. Fortunately, effective antifungal drugs can treat almost all diseases. The main thing is to choose the right medicine.
How to choose an antifungal drug
A trivial but correct answer is to consult a doctor, who will make a diagnosis and prescribe medication. It is very easy to make a mistake when diagnosing yourself, because fungal infections are similar in symptoms to many other diseases. For example, the same "thrush" may be bacterial vaginosis, which requires a completely different therapy. In addition, we must remember that inappropriate long-term treatment worsens the course of the disease.
Fungal nail infections are the easiest to diagnose, although mistakes are also possible here. If you treat yourself, remember that ointments, gels and creams on the nails do not work, only liquids and varnishes. An important thing that many people do not take into account is that the affected part of the nail must be removed before using the medicine. If this is not done, the drug will not reach the lesion. If the matrix (active growth area of the nail) is damaged, therapy with tablets and injections is required along with local medications 4.
How to use anti-fungal varnish correctly
One of the important features of the use of antimycotic agents is that the nail plate should be as clean as possible. To do this, the fungal deposits are carefully removed using nail clippers. The nails themselves should be cut short, washed with laundry soap and treated with an alcohol solution.
Varnish is applied with a special brush included in the product kit on completely dry nails. Avoid contact with surrounding skin. In this case, it is important to follow the instructions. To improve the effect of the varnish, it is advisable to wear light cotton socks during the entire treatment, change them every day, and wide shoes that do not squeeze your toes.
The most effective remedy for toenail fungus
Nail fungus requires treatment at the earliest signs of the disease. The sooner the problem is diagnosed and the course is started, the greater the chance of successfully eliminating mycosis with minimal consequences. Even among the most effective remedies for nail fungus, you need to choose the most suitable option.
How to choose an effective remedy for nail fungus
Mycosis treatment is a long process. Sometimes dermatologists offer a choice of several options for drugs from the same pharmacological group. Given the price of modern antifungal drugs, a course of treatment often costs a lot of money.
Therefore, in some cases, it may be advisable, after consulting a doctor, to choose a cheaper drug analogue with the same or similar active ingredient in its pharmacological properties. In order not to make a mistake in choosing, it is worth taking into account patient reviews of the most popular drugs.
Pharmaceutical drugs for nail fungus are divided according to the method of application:
- external preparations intended for local treatment of the affected surface (spray, ointment, cream, varnish);
- internal preparations have a systemic antimycotic effect on the whole body (capsules, tablets).
There are many pathogenic species among fungi, and the exact cause of the disease will be determined by the doctor after taking the analysis. In further cases, the analysis may show several pathogenic fungi, and each of them requires its own medicine.
How to determine if your nails are affected by fungus
Nail fungus is characterized by inflammation, pain and swelling of the finger, as well as yellowness and collapse of the nail itself. The nails appear deformed with inflamed skin and periungual ridges. There is delamination and fragility of the nails, the fingers look unkempt. In advanced cases, the tissue begins to die and expose the base of the nail.
What group of antifungal agents exist for nail fungus?
Among the mycoses there are diseases that are difficult to control with a tendency to relapse. If you violate the treatment regimen and stop the course as soon as the visible symptoms of the disease disappear, the lesion will return in a more complex form and it will be more difficult to get rid of it.
When treated with any drug, even the most expensive, you cannot survive with just one pill, nail fungus requires time and patience.
It is not advised to self-medicate; at the first sign of nail fungus, you should visit a dermatologist.
azole group
Antimycotic agents based on imidazole and triazole active ingredients have a double effect:
- fungicidal - destroys pathogenic cells;
- fungistatic - destroys fungal spores and prevents them from multiplying.
This product shows good activity against yeast, mold and yeast-like fungi. Medicines of the azole group are available in different forms: for oral administration - tablets and capsules, external forms - ointments, creams, varnishes, solutions.
Capsules and tablets are taken as prescribed by the attending physician according to the recommended regimen. Usually this is a continuous course, but other treatment regimens are possible, scheduled over several months (up to six months) while healthy nails grow. Ointments and creams are applied to the affected nail plate several times a day.
Before the treatment, you should first cut your nails at the root and make a soda soap bath for your feet.
Allylamine group
Drugs based on allylamines quickly eliminate the unpleasant symptoms of fungal nail infection: burning and itching. The active ingredient is active against fungi of the genus Candida, dermatophytes, as well as molds; pathogens are destroyed by destroying their cell membranes.
Creams and sprays are applied to the affected nails 1-2 times a day after hygiene procedures: cutting nails, soapy bath, thorough drying.
For local treatment, it makes sense to use drugs from the allylamine group if the pathogen affects less than half of the surface of the nail plate and the matrix is not affected. Otherwise, systemic tablets are indicated to destroy the infection.
The medicine must be applied to the surface, touching the surrounding skin.
Morpholine group
Drugs from the morpholine group contain amorolfine as the main active ingredient. The simplest form of medicine from this group is considered to be varnish.
Varnish is applied to the affected nail and does not fade for 1-2 weeks; new layers are periodically applied over the old ones.
Before coating, the affected nail surface must be steamed, dried well and degreased. When treating nails with anti-fungal varnish, be sure to observe strict hygiene measures: use only disposable files, disinfect spatulas.
Preparations from the morpholine group show good effectiveness against various types of fungi, penetrate the nail plate and begin to act quickly. Until the nail is fully restored, the course of treatment can last 9-12 months.